No, not where to get what some of you guys are on.
My book is set in the early 1900s at a time when certain drugs were used to cure headaches, such as cocaine. When I publish it, are the Kindle bots going to reject it out of hand? Should I try to disguise the names of the drugs?
Freud used drugs. Many doctors back then experimented on themselves. They found painkillers that way. You should be able to look up that stuff on the Net. PBS had programs about doctors in the 1800s experimenting with drugs, using themselves as test patients.
Good one, I'll remember that. The thing is, I want my readers to understand so if I call it opium, they will. Laudanum -- they would have to look up, most likely. I did some research on early drug stores and they used to put a pinch of it in sodas to cure headaches and other ailments. Our forefather were on the stuff quite often until somebody figured the people were buying way too many sodas.
Let's put it this way, o/p; my first two novels are set in the 1990s. They include very explicit descriptions of drug use by teenagers, including marijuana, ecstasy and copious amounts of alcohol.
I have yet to hear a peep out of anything remotely resembling a bot. I do include a content warning with my blurb.
Most of the drugs we now consider "illicit" were quite legal in the US up until the 1930s. Ex was employed by therapists in the 70s to help people with social anxiety and intimacy issues. Many of these other "drugs" were considered theraputic and helpful at one time or another--some of them still are, legal or not.
So, don't worry about including descriptions of drug use in historical fiction. There is absolutely no problem.